The Hamsa is a palm-shaped amulet popular throughout the Middle East and North Africa, and commonly used in jewelry and wall hangings. Depicting the open right hand, an image recognized and used as a sign of . It has come to be a symbol of secularity, and a trendy talisman; a " good luck " charm appearing on Tanit · Hamsa (disambiguation) · Khamsa. The hand is a powerful symbol of good luck in nearly every Mediterranean culture. In Muslim countries, the hand is made with the thumb and. People cross their index finger and middle finger, sometimes on both hands. Generally it has the meaning of wishing for good luck or good fortune. Alternately.